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USA & Canada: 1-800-935-9444
Outside the USA or Canada: 636-432-1455

  • Featured Destinations

    Featured Destination

    Caribbean

    ArubaBahamasBarbados
    Dominican RepublicGrand CaymanJamaica
    Puerto RicoSt. MaartenSt Thomas
    Turks & Caicos  

    Mexico

    Baja CaliforniaCancúnPuerto Vallarta
    Riviera Maya  

    United States

    • All Destinations
    • California
    • Florida
    • Hawaii

    Alaska

    Big Island, Hawaii

    Fort Lauderdale

    Kauai, Hawaii

    Key Largo

    Las Vegas

    Los Angeles

    Maui, Hawaii

    Miami

    New Orleans

    New York

    Oahu, Hawaii

    Orlando

    San Diego

    San Francisco

    Los AngelesSan DiegoSan Francisco

    Fort Lauderdale

    Key Largo

    Miami

    Orlando

      
    Big Island, HawaiiKauai, HawaiiMaui, Hawaii
    Oahu, Hawaii  
  • Airline Partners

    Our Airline Partners

  • Tours

    Tours

    5 Day Yellowstone National Park Getaway from Amtrak Vacations

    The captivating beauty and majesty of Yellowstone can only truly be described by those who have visited. During your five-day Getaway Roundtrip rail journey from Salt Lake City, you’ll experience why it is one of America’s most beloved national parks. 

    Destination Tour Packages

    Open Skies Interline Vacations have teamed up with the tour industry pros at Viator and GetYourGuide.com to bring you an assortment of tours and activities to help you get the most out of your next vacation!

    See some of our top picks under each featured destination, or search your own below!

  • Travel Resources Hub

NEW: Book Full Fare Flights, Hotels & Car Rentals!

Read more about the article Walt Disney World Resort Specials

Walt Disney World Resort Specials

  • Post author:Sean Wilburn
  • Post published:October 17, 2020
  • Post category:America/Orlando

Continue ReadingWalt Disney World Resort Specials
Read more about the article Sheraton San Diego Hotel & Marina

Sheraton San Diego Hotel & Marina

  • Post author:Sean Wilburn
  • Post published:October 17, 2020
  • Post category:America/San Diego

4 Days/3 Nights – Flexible Departure Dates.  Contact Us for Current Pricing! Sheraton San Diego Hotel & Marina Departures Any Day 4 Days/3 Nights from $399*Contact Us for Rates From Your Home City…

Continue ReadingSheraton San Diego Hotel & Marina
Read more about the article The Equus, an Ascend Collection Hotel

The Equus, an Ascend Collection Hotel

  • Post author:Sean Wilburn
  • Post published:October 13, 2020
  • Post category:America/Oahu

4 Days/3 Nights – Flexible Departure Dates.  Contact Us for Current Pricing! The Equus, an Ascend Collection Hotel 4 Days/3 Nights from $399*Flexible Departure Dates. Contact Us for Rates From Your Home…

Continue ReadingThe Equus, an Ascend Collection Hotel
Read more about the article Paramount Hotel New York

Paramount Hotel New York

  • Post author:Sean Wilburn
  • Post published:October 12, 2020
  • Post category:America/New York

4 Days/3 Nights – Flexible Departure Dates.  Contact Us for Current Pricing! New York Paramount Hotel Departures Any Day 4 Days/3 Nights from $349*Contact Us for Rates From Your Home City or for…

Continue ReadingParamount Hotel New York
Read more about the article Old No 77 Hotel & Chandlery

Old No 77 Hotel & Chandlery

  • Post author:Sean Wilburn
  • Post published:October 12, 2020
  • Post category:America/New Orleans

4 Days/3 Nights – Flexible Departure Dates.  Contact Us for Current Pricing! Old No. 77 Hotel & Chandlery Departures Any Day4 Days/3 Nights from $239*Contact Us for Rates From Your Home City…

Continue ReadingOld No 77 Hotel & Chandlery
Read more about the article Walt Disney World Dolphin Resort

Walt Disney World Dolphin Resort

  • Post author:Sean Wilburn
  • Post published:October 11, 2020
  • Post category:America/Orlando

4 Days/3 Nights – Flexible Departure Dates.  Contact Us for Current Pricing! Walt Disney World Dolphin Resort 4 Days/3 Nights – Flexible Departure Dates.  Contact Us for Current Pricing! ORLANDO…

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Read more about the article Radisson Hotel Lake Buena Vista

Radisson Hotel Lake Buena Vista

  • Post author:Sean Wilburn
  • Post published:October 11, 2020
  • Post category:America/Orlando

4 Days/3 Nights – Flexible Departure Dates.  Contact Us for Current Pricing! Radisson Hotel Lake Buena Vista Departures Any Day 4 Days/3 Nights from $249*Contact Us for Rates From Your Home City or…

Continue ReadingRadisson Hotel Lake Buena Vista
Read more about the article Cavalier Hotel South Beach

Cavalier Hotel South Beach

  • Post author:Sean Wilburn
  • Post published:October 10, 2020
  • Post category:America/Miami

4 Days/3 Nights – Flexible Departure Dates.  Contact Us for Current Pricing! Cavalier Hotel South Beach Departures Any Day 4 Days/3 Nights from $329*Contact Us for Rates From Your Home City or for…

Continue ReadingCavalier Hotel South Beach
Read more about the article Playa Largo Resort & Spa

Playa Largo Resort & Spa

  • Post author:Sean Wilburn
  • Post published:October 10, 2020
  • Post category:America/Key Largo

4 Days/3 Nights – Flexible Departure Dates.  Contact Us for Current Pricing! Playa Largo Resort & Spa Departures Any Day 4 Days/3 Nights from $699*Contact Us for Rates From Your Home City or…

Continue ReadingPlaya Largo Resort & Spa
Read more about the article Sonesta Fort Lauderdale Beach

Sonesta Fort Lauderdale Beach

  • Post author:Sean Wilburn
  • Post published:October 9, 2020
  • Post category:America/Fort Lauderdale

4 Days/3 Nights – Flexible Departure Dates.  Contact Us for Current Pricing! Sonesta Fort Lauderdale Beach Departures Any Day 4 Days/3 Nights from $389*Contact Us for Rates From Your Home City or for…

Continue ReadingSonesta Fort Lauderdale Beach
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Open Skies Vacations
3021 Highway A, Suite 103
Washington, MO U.S.A. 63090

USA & Canada: 
1-800-935-9444 
Outside the USA or Canada:
636-432-1455

Fax:
636-432-1459

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